Pharmacology (2)

Pharmacology (2)

Drugs Affecting central nervous system practice test [As you grow,the beauty steals inward]

published on November 14, 2012280 responses 0

which of following BARB are lowerly lipid soluble?

long acting
short acting
ultra short acting

BARB are being replaced by bensodiazepines (BZ) for clinical use as sedative hypnotic agents b/c of the following short comings ?

a narrow therapeutic index, shortening REMS and hight potential for
physical dependence
induction of seizures and shortening REMS
Induction of seizures and a narrow therapeutic index

which of the following drug is benzodiazepine causes sedation?

chlordiazepoxide
diazepam
flurazepam

the clinical uses of phenytoin include all of the following except?

grand mal seizure
psychomotor seizure
localizied seizure
minor seizure

classification of parkinsonian disorders drugs are?

Select the six correct answers
dopaminomimetic) metabolite precursor:levodopa
dopaminomimetic) decarboxylase inhibitor:carbidopa
dopaminomimetic) DA receptor agonist: bromocriptine
dopaminomimetic) MAO inhibitor: selegiline
dopaminomimetic) COMT inhibitor: tocapone
dopaminomimetic) drug releasing dopamine: amantadine
anticholinergic drug: trihexyphenidy

which drug is used for absence epilepsy as a second choice?

sodium valporate
BZ
MgSO4

A patient suffering from toxication due to overdosage of barbiturates should be adminstered?

intravenous infusion of NaHCO3
respiratory stimulant
cardiovascular stimulant
diuretics
all of above

which of the following drug in BZ is used for muscle relaxation?

diazepam
chlonazepam
flurazepam

intravenous anesthesia which drug is used?

thiopeutal
phenobarbital
amobarbital

uses of trihexayphendiyl?

Select the two correct answers
alone for mild patients: patients of discontinuation L-dopa due to
adverse effects
all parkinson's disorders: in combination with L-dopa
not alone for mild patients: patients of discontinuation L-dopa due to
adverse effects

therapeutic uses of levodopa?

Select the two correct answers
effective for parkinsonian disease and syndrome
combination with L-dopa and carbidopa
effective only for parkinsonian disease

the pharmacological effects of barbiturates include?

sedation
hypnosis
anticonvulsion
antiepileptism
all of the above

which of the following drug is used in BZ for terminating grand mal and status epilepsy?

diazepam
chlonazepam
flurazepam

which of the following drugs are lipophilic and rapidly absorbed by oral administration?

BZ
barbiturates
MgSO4

which of the following drugs are used as first choice in children's and infants?

barbiturates
BZ
seccineamide

drug used in myoclonic seizure and absence in children?

chlonazepam
carbamizepam
diazepam

characteristics of sleep induced by barbiturates is?

to shorten SEMS
to shorten REMS
to prolong SEMS
to prolong REMS
to shorten REMS and SEMS

adverse effects of amantadine?

Select the three correct answers
agitation and confusion
restlessness
hallucination

the pharmacological effects of bensodiazepines include all of the following except?

antianxiety
sedation
hypnosis
anticonvulsion
anesthesia

benzodiazepine includes?

chlordiazepoxide and diazepam
thiopental and hlordiazepoxide
L-dopa and carbidopa

drugs used in simple partial and grand mal epilepsy?

BZ
phenytoin
succineamide
barbiturates

drug effective for all parsial seizurs?

diazepam
carbamizepam
chlonazepam

which of the followings are true about parkinsonian disorders?

Select the three correct answers
tremor,muscular rigdety,bradykinesia
therapy: restablish dopamine/ Ach balance,to increase function of
dopaminergic neurons in nuostratium,to decrease function of
cholinergic neurons
clinical effects: relieving symptoms, not stopping progress
clinical effects: stopping progress

which are true about pharmacokinetics of Leodopa?

Select the two correct answers
doesnt cross BBB
well absorbed from small intestine and 90% decarboxylated in periphral
and results in peripheral side effect
cross BBB

which of the following drug is benzodiazepine causes anti anxiety?

Florazepam and temazepam
chloradiazepoxide and diazepam
chlorazepam and diazepam

trihexayphenidyl?

Select the three correct answers
less efficious than levodopa
more effictive in tremor
less effective in bradykinesia and rigidity

amantadine?

Select the three correct answers
stimulating synthesis and release of dopamine from surviving dopamine
nerve terminals
more effective than anti cholinergic agents
not effective for tremors
more effective than L-dopa in parkinson's disorder

which of the following drugs are used for anti Anxeity?

BZ
Barbiturates
MgSO4

pharmacological effecs of BZ includes?

sedation
antianxiety
hypnosis
anticonvulsion
all of the abvoe

which of the following drug is used for myoclonic sezure?

sodium valporate
MgSO4
BZ

which of the following drug cause small reduction in REM sleep?

chloralhydrate
paraldehydrate
phenobarbital

which of the following drugs in BZ is used for hypnosis?

flurazepam,temazepam,triazolam
chloradiazepoxide and diazepam
diazepam and flurazepam

which of the following drug is used to treat grand mal epilepsy,partial epilepsy,anti peripheral neuralgia,antiarrhythmia?

phenytoin
barbiturate
succineamide

due to following shortcomings benzodiazepines replaces BARB except?

a narrow therapeutic index
shortening REMS
induction of seizures
hight potential for physical dependence

benzodiazepine causes anti-anxiety at?

sedative dose
small dose
large dose

adverse effect of levodopa?

Select the three correct answers
tachycardia,arrythmia
vivid dream,mental disturbance,GIT(nausea vomiting)
no vit B6 during therapy
vit B6 during therapy

which drug is used often for minor or absence seizure?

succineamide
barbiturate
phenytoin

patients with hepatic and renal failure can use?

paraldehyde
chloralhydrate
phenobarbital

for antiepileptisum which drug can be used?

phenobarbital
thiopental
pentobarbital

which of the following is the first choice for epileticism in adult?

phenytoin
phenobarbital
oral diazepam
magnesium sulfate injection
all of the above

carbidopa?

Select the four correct answers
inhibitor of dopa decarboxylase
reduce peripheral conversion of L-dopa to dopamine
uses: combination with L-dopa
its not used alone
can use alone

which of the following BARB are highly lipid soluble?

ultra short acting barbiturates
long acting
short acting

uses of amantadine?

Select the one correct answers
do not use alone for early parkinson's disease
alone used for early parkinson's disease
various parkinson's diseases: in combination with L-dopa

which of the following drug in BZ is used for chronic epilepsy?

diazepam
chlonazepam
flurazepame