Pharmacology (2)

Pharmacology (2)

Drugs Affecting central nervous system practice test [As you grow,the beauty steals inward]

published on November 14, 201215 responses 0
Pharmacology (2)
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1/44

drugs used in simple partial and grand mal epilepsy?

BZ
phenytoin
succineamide
barbiturates
2/44

which of the following drug cause small reduction in REM sleep?

chloralhydrate
paraldehydrate
phenobarbital
3/44

pharmacological effecs of BZ includes?

sedation
antianxiety
hypnosis
anticonvulsion
all of the abvoe
4/44

therapeutic uses of levodopa?

Hint: 2 choices
effective for parkinsonian disease and syndrome
combination with L-dopa and carbidopa
effective only for parkinsonian disease
5/44

A patient suffering from toxication due to overdosage of barbiturates should be adminstered?

intravenous infusion of NaHCO3
respiratory stimulant
cardiovascular stimulant
diuretics
all of above
6/44

drug used in myoclonic seizure and absence in children?

chlonazepam
carbamizepam
diazepam
7/44

classification of parkinsonian disorders drugs are?

Hint: 6 choices
dopaminomimetic) metabolite precursor:levodopa
dopaminomimetic) decarboxylase inhibitor:carbidopa
dopaminomimetic) DA receptor agonist: bromocriptine
dopaminomimetic) MAO inhibitor: selegiline
dopaminomimetic) COMT inhibitor: tocapone
dopaminomimetic) drug releasing dopamine: amantadine
anticholinergic drug: trihexyphenidy
8/44

intravenous anesthesia which drug is used?

thiopeutal
phenobarbital
amobarbital
9/44

which of the following drugs in BZ is used for hypnosis?

flurazepam,temazepam,triazolam
chloradiazepoxide and diazepam
diazepam and flurazepam
10/44

which of the following drug in BZ is used for chronic epilepsy?

diazepam
chlonazepam
flurazepame
11/44

which of the following drug in BZ is used for muscle relaxation?

diazepam
chlonazepam
flurazepam
12/44

patients with hepatic and renal failure can use?

paraldehyde
chloralhydrate
phenobarbital
13/44

the pharmacological effects of barbiturates include?

sedation
hypnosis
anticonvulsion
antiepileptism
all of the above
14/44

benzodiazepine causes anti-anxiety at?

sedative dose
small dose
large dose
15/44

which of the following drug is benzodiazepine causes anti anxiety?

Florazepam and temazepam
chloradiazepoxide and diazepam
chlorazepam and diazepam
16/44

which of the following drugs are used for anti Anxeity?

BZ
Barbiturates
MgSO4
17/44

uses of amantadine?

Hint: 1 choice
do not use alone for early parkinson's disease
alone used for early parkinson's disease
various parkinson's diseases: in combination with L-dopa
18/44

which of the following drug is used in BZ for terminating grand mal and status epilepsy?

diazepam
chlonazepam
flurazepam
19/44

BARB are being replaced by bensodiazepines (BZ) for clinical use as sedative hypnotic agents b/c of the following short comings ?

a narrow therapeutic index, shortening REMS and hight potential for
physical dependence
induction of seizures and shortening REMS
Induction of seizures and a narrow therapeutic index
20/44

uses of trihexayphendiyl?

Hint: 2 choices
alone for mild patients: patients of discontinuation L-dopa due to
adverse effects
all parkinson's disorders: in combination with L-dopa
not alone for mild patients: patients of discontinuation L-dopa due to
adverse effects
21/44

which of the following is the first choice for epileticism in adult?

phenytoin
phenobarbital
oral diazepam
magnesium sulfate injection
all of the above
22/44

which of the following drugs are used as first choice in children's and infants?

barbiturates
BZ
seccineamide
23/44

which drug is used for absence epilepsy as a second choice?

sodium valporate
BZ
MgSO4
24/44

benzodiazepine includes?

chlordiazepoxide and diazepam
thiopental and hlordiazepoxide
L-dopa and carbidopa
25/44

which of the following drugs are lipophilic and rapidly absorbed by oral administration?

BZ
barbiturates
MgSO4
26/44

which of following BARB are lowerly lipid soluble?

long acting
short acting
ultra short acting
27/44

which drug is used often for minor or absence seizure?

succineamide
barbiturate
phenytoin
28/44

which of the following BARB are highly lipid soluble?

ultra short acting barbiturates
long acting
short acting
29/44

the clinical uses of phenytoin include all of the following except?

grand mal seizure
psychomotor seizure
localizied seizure
minor seizure
30/44

which of the followings are true about parkinsonian disorders?

Hint: 3 choices
tremor,muscular rigdety,bradykinesia
therapy: restablish dopamine/ Ach balance,to increase function of
dopaminergic neurons in nuostratium,to decrease function of
cholinergic neurons
clinical effects: relieving symptoms, not stopping progress
clinical effects: stopping progress
31/44

which are true about pharmacokinetics of Leodopa?

Hint: 2 choices
doesnt cross BBB
well absorbed from small intestine and 90% decarboxylated in periphral
and results in peripheral side effect
cross BBB
32/44

drug effective for all parsial seizurs?

diazepam
carbamizepam
chlonazepam
33/44

amantadine?

Hint: 3 choices
stimulating synthesis and release of dopamine from surviving dopamine
nerve terminals
more effective than anti cholinergic agents
not effective for tremors
more effective than L-dopa in parkinson's disorder
34/44

characteristics of sleep induced by barbiturates is?

to shorten SEMS
to shorten REMS
to prolong SEMS
to prolong REMS
to shorten REMS and SEMS
35/44

due to following shortcomings benzodiazepines replaces BARB except?

a narrow therapeutic index
shortening REMS
induction of seizures
hight potential for physical dependence
36/44

carbidopa?

Hint: 4 choices
inhibitor of dopa decarboxylase
reduce peripheral conversion of L-dopa to dopamine
uses: combination with L-dopa
its not used alone
can use alone
37/44

which of the following drug is used for myoclonic sezure?

sodium valporate
MgSO4
BZ
38/44

adverse effects of amantadine?

agitation and confusion
restlessness
hallucination
39/44

adverse effect of levodopa?

Hint: 3 choices
tachycardia,arrythmia
vivid dream,mental disturbance,GIT(nausea vomiting)
no vit B6 during therapy
vit B6 during therapy
40/44

for antiepileptisum which drug can be used?

phenobarbital
thiopental
pentobarbital
41/44

which of the following drug is benzodiazepine causes sedation?

chlordiazepoxide
diazepam
flurazepam
42/44

the pharmacological effects of bensodiazepines include all of the following except?

antianxiety
sedation
hypnosis
anticonvulsion
anesthesia
43/44

which of the following drug is used to treat grand mal epilepsy,partial epilepsy,anti peripheral neuralgia,antiarrhythmia?

phenytoin
barbiturate
succineamide
44/44

trihexayphenidyl?

less efficious than levodopa
more effictive in tremor
less effective in bradykinesia and rigidity