Reproductive Pharmacology

Reproductive Pharmacology

Quiz focuses on reproductive drugs, namely the oestrogens, progestins and androgens. Selective modulators and therapies linked to these hormones will be discussed.

published on April 14, 2013114 responses 0

Which of the following drugs is used to treat infertility?

Tamoxifen
Ethinyl estradiol
Clomiphene
Raloxifene

What is the mechanism of action of sildenafil?

It is a vasodilator, increasing bloodflow to the corpus cavernosum.
It is a L-type calcium channel blocker, reducing influx of calcium from
smooth muscle stores.
It is an alpha-1 AR agonist, dilating blood vessels to increase vascular
flow to corpus cavernosum
It inhibits phosphodiesterase 5, preventing conversion of cGMP to 5'
GMP, lowering iCa stores, relaxing the smooth muscle.

What is the principle of using estrogen and progestin as contraceptives?

Estrogen binds to the ER receptor in the anterior pituitary, inhibiting
release of FSH. Progestin also inhibits the ER receptor of the anterior
pituitary.
Estrogen binds to the ER receptor in the anterior pituitary, inhibiting
release of FSH. Progestin also reduces frequency of GnRH release
from the hypothalamus.
Estrogen binds to the ER receptor in the anterior pituitary, inhibiting
release of FSH. Progestin reduces frequency of LH release from the
anterior pituitary.
Estrogen reduces frequency of LH release from the anterior pituitary.
Progestin inhibits FSH secretion from the hypothalamus.

Which of the following is NOT a side effect of the hormone oestrogen?

Acne
Thromboembolism
Osteoporosis
Migraine

Which of the following are examples of female long term contraceptives?

Norethindrone
Norgestrel
Levonorgestral
Finasteride